- 1.332SOCS
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(= suppressor of cytokine signalling)Family of proteins (SOCS 1-3 and CIS; 211 amino acids) rapidly induced in response to IL-6 and other cytokines, thought to act as negative feedback regulator of JAKs in the intracellular signalling pathway. All contain a central SH2domain. Similar, possibly identical, to JAB and SSI-1.
Dictionary of molecular biology. 2004.